Treating mice with isradipine, a calcium channel blocker, prevented formation of toxic compounds that can cause Parkinson’s disease symptoms, according to a recent Northwestern Medicine study.
Northwestern Medicine scientists used an innovative technique to measure electrical activity in ALS neurons, finding changes in excitability that indicated disease, according to a study published in Stem Cell Reports.
Feinberg met its goal of raising $10 million for the newly renamed Mesulam Cognitive Neurology and Alzheimer’s Disease Center, naming the Center after its director, M. Marsel Mesulam, MD.
Northwestern scientists restored chemical balance to certain brain cells in mouse models, reversing mechanisms that may be responsible for sensory hypersensitivity in patients with autism.
The newly-launched Center for Autism and Neurodevelopment is a translational science hub that aims to investigate the neurobiology of autism and facilitate the development of new treatments.
Northwestern Medicine scientists have uncovered how DNA methylation triggers stem cells to transform into more specialized neuronal cells.
The mission of the Center is to catalyze scientific collaborations aimed at understanding the biological bases of autism and related neurodevelopmental disorders, and to translate those findings into new treatments.
Q & A with Mark Bevan, PhD, professor of Physiology
The brain’s own mechanisms for dealing with the loss of dopamine neurons in Parkinson’s disease may be a source of the disorder’s abnormal movement, according to a Northwestern Medicine study published in Neuron.
Northwestern Medicine scientists have identified a toxic cascade that leads to neuronal degeneration in patients with Parkinson’s disease (PD), findings published in the journal Science.
Northwestern Medicine scientists have demonstrated a new method that helps to pinpoint which genetic variants might be most important in the development of schizophrenia and related disorders.
Northwestern Medicine scientists and co-authors defined a role for the WAVE1 protein in the cellular mechanisms behind cocaine addiction.
New Northwestern Medicine research shows how astrocytes, a type of cell in the brain, may play a role in regulating a pathway that is overactive in Parkinson’s disease.
By targeting a hub of schizophrenia-related genes, Northwestern Medicine scientists were able to correct a disease-related alteration in mouse model neurons.
Certain anatomical properties of the brain – not the initial injury – determine most of a patient’s risk of developing chronic pain, according to a new study.
Genetic mutations that cause neuropsychiatric disorders may make synapses smaller and weaker, according to a new Northwestern Medicine study.
Northwestern Medicine scientists mapped brain circuitry associated with addiction and reward, and found that smoking affects the way the brain relates and responds to pain. The findings could lead to targeted therapies for chronic pain sufferers.
Northwestern Medicine scientists have proven an old therapeutic focus for Huntington's disease wrong, and they propose a new one in its place.
The experimental drug prolonged the lifespan in a mouse model of accelerated aging by inhibiting a protein that plays a key role in the process.
Tanya Simuni, MD, was awarded a grant from the National Institutes of Health to conduct a $16 million phase III study of the safety and efficacy of the drug isradipine as a potential neuroprotective agent in Parkinson's disease.
Acclaimed physiologist and expert in the biomechanics of skeletal muscle will arrive at the Rehabilitation Institute of Chicago and Northwestern University Feinberg School of Medicine later this year.
Lauren Smith, a sixth-year MD/PhD student, is the recipient of a Presidential Fellowship, the most prestigious fellowship awarded to graduate students at Northwestern. Her research focuses on improving the control of myoelectric upper limb prostheses. She works in the labs of Todd Kuiken, MD, PhD, and Levi Hargrove, PhD.
With its recent renewal, Feinberg's Udall Center of Excellence for Parkinson's Disease Research is one of 10 such centers funded by the National Institute of Neurological Disorders and Stroke.
Anis Contractor, PhD, associate professor in Physiology, recently published findings on what causes delays in synaptic and neuronal development in the cortex, hallmarks of fragile X syndrome, the most common known cause of autism.